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Effects of different concentrations of DO on the content of <t>VEGF</t> (A) and MMP‐9 (B) in the skin tissue of mice after incision injury. # p < 0.05, ### p < 0.001 vs. BC group; * p < 0.05, ** p < 0.01, *** p < 0.001 vs. NC group.
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Effects of <t>DQJD‐mediated</t> <t>RXR‐γ/PPAR‐γ/VEGF‐α</t> activation in CCH‐induced rats. (A) Representative immunoblots of cortical RXR‐γ, VEGF‐α and PPAR‐γ. GAPDH was used as a control reference protein. (B–D) Data were expressed as a multiple of the density change compared to the control tissue by Image J software (mean ± SD, n = 5), **** p < 0.0001 (versus control); # p < 0.05 (versus model); ## p < 0.01 (versus model); ### p < 0.001 (versus model). PPAR‐γ, Peroxisome proliferator‐activated receptor gamma; RXR‐γ, Retinoid × receptor gamma; VEGF‐α, Vascular endothelial growth factor α.
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Effects of <t>DQJD‐mediated</t> <t>RXR‐γ/PPAR‐γ/VEGF‐α</t> activation in CCH‐induced rats. (A) Representative immunoblots of cortical RXR‐γ, VEGF‐α and PPAR‐γ. GAPDH was used as a control reference protein. (B–D) Data were expressed as a multiple of the density change compared to the control tissue by Image J software (mean ± SD, n = 5), **** p < 0.0001 (versus control); # p < 0.05 (versus model); ## p < 0.01 (versus model); ### p < 0.001 (versus model). PPAR‐γ, Peroxisome proliferator‐activated receptor gamma; RXR‐γ, Retinoid × receptor gamma; VEGF‐α, Vascular endothelial growth factor α.
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Inflammatory and angiogenesis biomarkers in parameters in the serum of nude mice after the treatment with TQ and 5‐FU.
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Image Search Results


Effects of different concentrations of DO on the content of VEGF (A) and MMP‐9 (B) in the skin tissue of mice after incision injury. # p < 0.05, ### p < 0.001 vs. BC group; * p < 0.05, ** p < 0.01, *** p < 0.001 vs. NC group.

Journal: Journal of Cosmetic Dermatology

Article Title: Protective Effects of Exogenous Donkey Oil on Skin Healing Under Incisional Wound Damage

doi: 10.1111/jocd.70550

Figure Lengend Snippet: Effects of different concentrations of DO on the content of VEGF (A) and MMP‐9 (B) in the skin tissue of mice after incision injury. # p < 0.05, ### p < 0.001 vs. BC group; * p < 0.05, ** p < 0.01, *** p < 0.001 vs. NC group.

Article Snippet: The ELISA kits IL‐1α and VEGF were purchased from ProteinTech (Wuhan, China, Cat No: KE10024 and KE10009); IL‐6 from Multi Sciences (Hangzhou, China, Cat No: EK206/3‐96); PGE2 from Lanpaibio (Shanghai, China, Cat No: LP‐M05161); MMP‐9 from CUSABIO (Wuhan, China, Cat No: CSB‐E08007m).

Techniques:

Effects of DQJD‐mediated RXR‐γ/PPAR‐γ/VEGF‐α activation in CCH‐induced rats. (A) Representative immunoblots of cortical RXR‐γ, VEGF‐α and PPAR‐γ. GAPDH was used as a control reference protein. (B–D) Data were expressed as a multiple of the density change compared to the control tissue by Image J software (mean ± SD, n = 5), **** p < 0.0001 (versus control); # p < 0.05 (versus model); ## p < 0.01 (versus model); ### p < 0.001 (versus model). PPAR‐γ, Peroxisome proliferator‐activated receptor gamma; RXR‐γ, Retinoid × receptor gamma; VEGF‐α, Vascular endothelial growth factor α.

Journal: Journal of Cellular and Molecular Medicine

Article Title: Daqinjiao Decoction Ameliorates CSVD via RXR‐γ/PPAR‐γ/VEGF‐α Pathway: Insights From Transcriptome Sequencing and Network Pharmacology

doi: 10.1111/jcmm.70712

Figure Lengend Snippet: Effects of DQJD‐mediated RXR‐γ/PPAR‐γ/VEGF‐α activation in CCH‐induced rats. (A) Representative immunoblots of cortical RXR‐γ, VEGF‐α and PPAR‐γ. GAPDH was used as a control reference protein. (B–D) Data were expressed as a multiple of the density change compared to the control tissue by Image J software (mean ± SD, n = 5), **** p < 0.0001 (versus control); # p < 0.05 (versus model); ## p < 0.01 (versus model); ### p < 0.001 (versus model). PPAR‐γ, Peroxisome proliferator‐activated receptor gamma; RXR‐γ, Retinoid × receptor gamma; VEGF‐α, Vascular endothelial growth factor α.

Article Snippet: The membrane was incubated with blocking buffer for 5 min at room temperature and washed by adding the configured antibodies, VEGF‐α (1:1000, Proteintech), RXR‐γ (1:800, Proteintech) and PPAR‐γ (1:5000, Proteintech), incubated for 90 min at room temperature and washed for 10 min. ECL chemiluminescence (Solarbio, Beijing, China) was used to develop the bands.

Techniques: Activation Assay, Western Blot, Control, Software

The possible mechanism of DQJD on CSVD. DQJD has beneficial effects on improving inflammation and pathological damage in the cortex and hippocampus in the CSVD model. The mechanism of action may be related to the activation of the RXR‐γ/PPAR‐γ/VEGF signalling pathway.

Journal: Journal of Cellular and Molecular Medicine

Article Title: Daqinjiao Decoction Ameliorates CSVD via RXR‐γ/PPAR‐γ/VEGF‐α Pathway: Insights From Transcriptome Sequencing and Network Pharmacology

doi: 10.1111/jcmm.70712

Figure Lengend Snippet: The possible mechanism of DQJD on CSVD. DQJD has beneficial effects on improving inflammation and pathological damage in the cortex and hippocampus in the CSVD model. The mechanism of action may be related to the activation of the RXR‐γ/PPAR‐γ/VEGF signalling pathway.

Article Snippet: The membrane was incubated with blocking buffer for 5 min at room temperature and washed by adding the configured antibodies, VEGF‐α (1:1000, Proteintech), RXR‐γ (1:800, Proteintech) and PPAR‐γ (1:5000, Proteintech), incubated for 90 min at room temperature and washed for 10 min. ECL chemiluminescence (Solarbio, Beijing, China) was used to develop the bands.

Techniques: Activation Assay

Inflammatory and angiogenesis biomarkers in parameters in the serum of nude mice after the treatment with TQ and 5‐FU.

Journal: Journal of Biochemical and Molecular Toxicology

Article Title: Combination of 5‐Fluorouracil and Thymoquinone for Enhanced Cytotoxicity, Genotoxicity and Apoptosis In Colorectal Cancer: In Vitro and In Vivo Studies

doi: 10.1002/jbt.70276

Figure Lengend Snippet: Inflammatory and angiogenesis biomarkers in parameters in the serum of nude mice after the treatment with TQ and 5‐FU.

Article Snippet: After protein determination in tissue homogenates, TGFβ1 (E‐EL‐M0051, Elabscience, USA) and VEGF‐α (E‐EL‐M1292, Elabscience, USA) levels were measured by photometric analysis using commercially purchased mouse ELISA kits.

Techniques: Negative Control, Positive Control

Pro‐inflammatory and angiogenesis biomarkers in parameters on tissue of nude mice after the treatment with TQ and 5‐FU.

Journal: Journal of Biochemical and Molecular Toxicology

Article Title: Combination of 5‐Fluorouracil and Thymoquinone for Enhanced Cytotoxicity, Genotoxicity and Apoptosis In Colorectal Cancer: In Vitro and In Vivo Studies

doi: 10.1002/jbt.70276

Figure Lengend Snippet: Pro‐inflammatory and angiogenesis biomarkers in parameters on tissue of nude mice after the treatment with TQ and 5‐FU.

Article Snippet: After protein determination in tissue homogenates, TGFβ1 (E‐EL‐M0051, Elabscience, USA) and VEGF‐α (E‐EL‐M1292, Elabscience, USA) levels were measured by photometric analysis using commercially purchased mouse ELISA kits.

Techniques: Control